Noninvasive Cancer Research

Telomerase Inhibitor Therapy

Telomerase therapy is a revolutionary technology that can kill cancer by stopping the production of cancer cells without harming other cells. When a cell contains telomerase it re-lengthens telomeres which are a repeating DNA structure at the ends of each chromosome that shorten with each cell division and eventually kills the cell. Cancer cells are immortal because they contain telomerase which allows the cancerous cells to continually divide and replicate without limit.

Telomerase inhibitors have been successfully proven to limit or kill the growth of various kinds of cancer cells by shortening its telomeres.  The set back to this technology has been an effective delivery of the telomerase inhibitor to cancerous cells. Vanguard is researching various methods and believes to have found an effective method.



Low Power Radio Frequency Radiation (Radiosurgery):

Precisely delivers large radiation doses to targeted cancer cells and tumors. This non invasive procedure destroys or makes inactive the cancer without harming nearby healthy tissue and does not require traditional surgery.  

A group of scientists from the University of Arkansas have killed 98% of cervical cancer cells by using nano-sized cobalt particle in graphitic carbon layers inside the cells and then thermally activate them with radio surgery. Radio surgery has lots of potential in becoming the new common cancer treatment.

Anti-ageing Telomerase Research

Telomerase therapy can also be used to restore the ability of cells in aged tissues to regenerate and heal. Normal body cells are mortal and slow down when their telomeres shorten. They do not contain telomerase to keep them youthful. Telomerase activators have shown to increase telomere length which can restore skins youthful appearance and can heal arthritic joints or cardiovascular tissue.

As in the case of telomerase inhibitors the technology requires an effective delivery method that will allow both treatments to be effective. With an effective delivery method proven, this technology can then be used in cosmetic clinics and will allow the ageing population to restore age related skin signs.   



Chromosome Ends and Diseases of Aging - video

Generic Product Development

Vanguard's manufacturers have been and are leading the way in developing new generics. Its oncology manufacturer was:
• 2nd in India to launch Room Temperature Stable AMTAX (Paclitaxel Inj)
• 2nd in India to launch Room Temperature Stable & Ready to Use
.. COLODACH (Oxaliplatin Inj)
• 1st in India to launch Ready to Use RUBICAM (Epirubicin Inj)
• 1st in India to launch Ready to Use AMZOL (Zolendronic Acid Inj)

R&D Contracting

With increased pressure on profit margins, surging R&D costs, and increasing overheads, outsourcing of clinical research processes to third parties in developing countries is a viable option. Vanguard offers contracting of such work which will save pharmaceutical companies 40-60 % in new drug development. Its analytical services division specializes in spectroscopy, microscopy, chemical analysis and instrumental development to provide innovative solutions to client requirements.